The longest-running medical drama of all time, ER followed an ever-changing group of doctors and nurses at a fictional Chicago hospital called Cook County General Hospital. While it lasted from 1994 to 2009 and won an absurd 23 Primetime Emmys, this NBC mainstay really flourished in its first few seasons, since that was when we got George Clooney in a career-making role as Dr. Doug Ross. Based on an old Michael Crichton script he wrote about his time working in a hospital, some of the show's most famous episodes involved dealing with a nasty highway accident in the middle of a blizzard, Clooney rescuing a kid out of a storm drain, an attempted suicide by one of the ER's interns, and trying to salvage the survivors of a nasty chemical spill. But on top of all the medical action and behind the stethoscope drama, Mr. Skin was glued to the TV thanks to the anatomy of the foxy female denizens of County General. Julianna Margulies, Maura Tierney, Linda Cardellini, and Sherri Stringfield were just a few of the mouthwatering, medically inclined muffins who starred during ER's 15-season reign. They're so sexy, you'll go into cardiac arrest! But what really made ER special was how many guest stars went on to become famous. Christina Hendricks, Kat Dennings, Lake Bell, Leslie Bibb, Kirsten Dunst and more showed up on the show. But if we had to give out a best undressed guest title, the two contenders would be Mariska Hargitay and Liz Vassey. Miss Vassey gives us a little ass-see as a gorgeous woman suffering from a bad case of Poison Ivy. Seeing her bent over with her buns in the air as she flirtily tries to stiffen the cock of the young male doc, will scratch an itch you never knew you had! Mariska, on the other hand, played desk clerk Cynthia Hooper, who we get to watch unbutton a jacket to show her doctor boyfriend her new lingerie. We didn't realize that every woman wanted to play with your tool the minute you went to med school! If the show is to be believe, one shift in the ER is the fast track to hardER! HardER!